Sensitization of melanoma cells for TRAIL-induced apoptosis by BMS-345541 correlates with altered phosphorylation and activation of Bax

Resistance to TRAIL (TNF-related apoptosis-inducing ligand)- induced apoptosis limits its therapeutic use. Different strategies of TRAIL sensitization and a dependency on Bax have been reported, but common principles of TRAIL resistance and the way of Bax activation remained poorly understood. Apply...

Descripción completa

Detalles Bibliográficos
Autores principales: Berger, A, Quast, S-A, Plötz, M, Kammermeier, A, Eberle, J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563986/
https://www.ncbi.nlm.nih.gov/pubmed/23348591
http://dx.doi.org/10.1038/cddis.2012.198

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563986/
https://www.ncbi.nlm.nih.gov/pubmed/23348591
http://dx.doi.org/10.1038/cddis.2012.198

Ejemplares similares