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Resveratrol potentiates rapamycin to prevent hyperinsulinemia and obesity in male mice on high fat diet
High doses of rapamycin, an antiaging agent, can prevent obesity in mice on high fat diet (HFD). Obesity is usually associated with hyperinsulinemia. Here, we showed that rapamycin given orally, at doses that did not affect weight gain in male mice on HFD, tended to decrease fasting insulin levels....
Autores principales: | Leontieva, O V, Paszkiewicz, G, Demidenko, Z N, Blagosklonny, M V |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563990/ https://www.ncbi.nlm.nih.gov/pubmed/23348586 http://dx.doi.org/10.1038/cddis.2012.202 |
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