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Drosophila Trap1 protects against mitochondrial dysfunction in a PINK1/parkin model of Parkinson's disease

Mitochondrial dysfunction caused by protein aggregation has been shown to have an important role in neurological diseases, such as Parkinson's disease (PD). Mitochondria have evolved at least two levels of defence mechanisms that ensure their integrity and the viability of their host cell. Firs...

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Detalles Bibliográficos
Autores principales: Costa, A C, Loh, S H Y, Martins, L Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3563993/
https://www.ncbi.nlm.nih.gov/pubmed/23328674
http://dx.doi.org/10.1038/cddis.2012.205