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Synergy between RA and TLR3 promotes type I IFN-dependent apoptosis through upregulation of TRAIL pathway in breast cancer cells

Due to its ability to regulate the growth, differentiation and apoptosis of cancer cells, retinoic acid (RA) is considered a signaling molecule with promising therapeutic potential in oncology. In this study, we show that RA is able to induce the intrinsic ability of breast cancer cells to recognize...

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Detalles Bibliográficos
Autores principales: Bernardo, A R, Cosgaya, J M, Aranda, A, Jiménez-Lara, A M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564005/
https://www.ncbi.nlm.nih.gov/pubmed/23370279
http://dx.doi.org/10.1038/cddis.2013.5