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Robust shifts in S100a9 expression with aging: A novel mechanism for chronic inflammation

The S100a8 and S100a9 genes encode a pro-inflammatory protein (calgranulin) that has been implicated in multiple diseases. However, involvement of S100a8/a9 in the basic mechanisms of intrinsic aging has not been established. In this study, we show that shifts in the abundance of S100a8 and S100a9 m...

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Detalles Bibliográficos
Autores principales: Swindell, William R., Johnston, Andrew, Xing, Xianying, Little, Andrew, Robichaud, Patrick, Voorhees, John J., Fisher, Gary, Gudjonsson, Johann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564041/
https://www.ncbi.nlm.nih.gov/pubmed/23386971
http://dx.doi.org/10.1038/srep01215