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GSK-3 and mitochondria in cancer cells

GSK-3 is a multifunctional kinase that is located in the cytosol, nucleus, and mitochondria of all cell types, and it is involved in the pathogenesis of a variety of diseases. In cancer, GSK-3 modulates the response of the cell death machinery to stress stimuli, including chemotherapeutics. Mitochon...

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Detalles Bibliográficos
Autores principales: Chiara, Federica, Rasola, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564062/
https://www.ncbi.nlm.nih.gov/pubmed/23386998
http://dx.doi.org/10.3389/fonc.2013.00016