Cargando…
Systematic analysis of somatic mutations in phosphorylation signaling predicts novel cancer drivers
Large-scale cancer genome sequencing has uncovered thousands of gene mutations, but distinguishing tumor driver genes from functionally neutral passenger mutations is a major challenge. We analyzed 800 cancer genomes of eight types to find single-nucleotide variants (SNVs) that precisely target phos...
| Autores principales: | , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2013
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564258/ https://www.ncbi.nlm.nih.gov/pubmed/23340843 http://dx.doi.org/10.1038/msb.2012.68 |