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Genome-wide analysis of FOXO3 mediated transcription regulation through RNA polymerase II profiling

Forkhead box O (FOXO) transcription factors are key players in diverse cellular processes affecting tumorigenesis, stem cell maintenance and lifespan. To gain insight into the mechanisms of FOXO-regulated target gene expression, we studied genome-wide effects of FOXO3 activation. Profiling RNA polym...

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Detalles Bibliográficos
Autores principales: Eijkelenboom, Astrid, Mokry, Michal, de Wit, Elzo, Smits, Lydia M, Polderman, Paulien E, van Triest, Miranda H, van Boxtel, Ruben, Schulze, Almut, de Laat, Wouter, Cuppen, Edwin, Burgering, Boudewijn M T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564262/
https://www.ncbi.nlm.nih.gov/pubmed/23340844
http://dx.doi.org/10.1038/msb.2012.74