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Histological grading of breast cancer on needle core biopsy: the role of immunohistochemical assessment of proliferation

AIMS: Histological grade assessed on needle core biopsy (NCB) moderately concurs with the grade in the surgical excision specimen (SES) (κ-values between 0.35 and 0.65). A major cause of the discrepancy is underestimation of mitoses in the NCB specimen. The aim was to determine the best method of as...

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Detalles Bibliográficos
Autores principales: Kwok, T’ng Chang, Rakha, Emad A, Lee, Andrew H S, Grainge, Matthew, Green, Andrew R, Ellis, Ian O, Powe, Desmond G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564399/
https://www.ncbi.nlm.nih.gov/pubmed/20716163
http://dx.doi.org/10.1111/j.1365-2559.2010.03620.x