In vivo SELEX for Identification of Brain-penetrating Aptamers

The physiological barriers of the brain impair drug delivery for treatment of many neurological disorders. One delivery approach that has not been investigated for their ability to penetrate the brain is RNA-based aptamers. These molecules can impart delivery to peripheral tissues and circulating im...

Descripción completa

Detalles Bibliográficos
Autores principales: Cheng, Congsheng, Chen, Yong Hong, Lennox, Kim A, Behlke, Mark A, Davidson, Beverly L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564417/
https://www.ncbi.nlm.nih.gov/pubmed/23299833
http://dx.doi.org/10.1038/mtna.2012.59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564417/
https://www.ncbi.nlm.nih.gov/pubmed/23299833
http://dx.doi.org/10.1038/mtna.2012.59

Ejemplares similares