Targeted Gene Addition of Microdystrophin in Mice Skeletal Muscle via Human Myoblast Transplantation

Zinc finger nucleases (ZFN) can facilitate targeted gene addition to the genome while minimizing the risks of insertional mutagenesis. Here, we used a previously characterized ZFN pair targeting the chemokine (C-C motif) receptor 5 (CCR5) locus to introduce, as a proof of concept, the enhanced green...

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Detalles Bibliográficos
Autores principales: Benabdallah, Basma F, Duval, Arnaud, Rousseau, Joel, Chapdelaine, Pierre, Holmes, Michael C, Haddad, Eli, Tremblay, Jacques P, Beauséjour, Christian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564421/
https://www.ncbi.nlm.nih.gov/pubmed/23360951
http://dx.doi.org/10.1038/mtna.2012.55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564421/
https://www.ncbi.nlm.nih.gov/pubmed/23360951
http://dx.doi.org/10.1038/mtna.2012.55

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