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Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage

The chemopreventive agent curcumin has anti-proliferative effects in many tumour types, but characterization of cell cycle arrest, particularly with physiologically relevant concentrations, is still incomplete. Following oral ingestion, the highest concentrations of curcumin are achievable in the gu...

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Detalles Bibliográficos
Autores principales: Blakemore, Louise M., Boes, Christoph, Cordell, Rebecca, Manson, Margaret M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564441/
https://www.ncbi.nlm.nih.gov/pubmed/23125222
http://dx.doi.org/10.1093/carcin/bgs345