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Curcumin-induced mitotic arrest is characterized by spindle abnormalities, defects in chromosomal congression and DNA damage
The chemopreventive agent curcumin has anti-proliferative effects in many tumour types, but characterization of cell cycle arrest, particularly with physiologically relevant concentrations, is still incomplete. Following oral ingestion, the highest concentrations of curcumin are achievable in the gu...
Autores principales: | Blakemore, Louise M., Boes, Christoph, Cordell, Rebecca, Manson, Margaret M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564441/ https://www.ncbi.nlm.nih.gov/pubmed/23125222 http://dx.doi.org/10.1093/carcin/bgs345 |
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