Time line of redox events in aging postmitotic cells

The precise roles that oxidants play in lifespan and aging are still unknown. Here, we report the discovery that chronologically aging yeast cells undergo a sudden redox collapse, which affects over 80% of identified thiol-containing proteins. We present evidence that this redox collapse is not trig...

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Detalles Bibliográficos
Autores principales: Brandes, Nicolas, Tienson, Heather, Lindemann, Antje, Vitvitsky, Victor, Reichmann, Dana, Banerjee, Ruma, Jakob, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2013
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564446/
https://www.ncbi.nlm.nih.gov/pubmed/23390587
http://dx.doi.org/10.7554/eLife.00306

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564446/
https://www.ncbi.nlm.nih.gov/pubmed/23390587
http://dx.doi.org/10.7554/eLife.00306

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