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Characterization, activity, and computer modeling of a molecular inclusion complex containing rifaldazine

BACKGROUND: The purpose of this study was to develop, characterize, and investigate a molecular inclusion complex containing rifaldazine with good solubility and antibacterial activity. METHODS: Rifaldazine, a lipophilic molecule, was encapsulated into the hydrophobic cavity of β-cyclodextrin to for...

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Detalles Bibliográficos
Autores principales: Tan, Qunyou, He, Dan, Wu, Mingjun, Yang, Lin, Ren, Yong, Liu, Juan, Zhang, Jingqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564462/
https://www.ncbi.nlm.nih.gov/pubmed/23390365
http://dx.doi.org/10.2147/IJN.S38937