The Rab27a effector exophilin7 promotes fusion of secretory granules that have not been docked to the plasma membrane

Granuphilin, an effector of the small GTPase Rab27a, mediates the stable attachment (docking) of insulin granules to the plasma membrane and inhibits subsequent fusion of docked granules, possibly through interaction with a fusion-inhibitory Munc18-1/syntaxin complex. However, phenotypes of insulin...

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Detalles Bibliográficos
Autores principales: Wang, Hao, Ishizaki, Ray, Xu, Jun, Kasai, Kazuo, Kobayashi, Eri, Gomi, Hiroshi, Izumi, Tetsuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564536/
https://www.ncbi.nlm.nih.gov/pubmed/23223571
http://dx.doi.org/10.1091/mbc.E12-04-0265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564536/
https://www.ncbi.nlm.nih.gov/pubmed/23223571
http://dx.doi.org/10.1091/mbc.E12-04-0265

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