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Lamin A tail modification by SUMO1 is disrupted by familial partial lipodystrophy–causing mutations
Lamin filaments are major components of the nucleoskeleton that bind LINC complexes and many nuclear membrane proteins. The tail domain of lamin A directly binds 21 known partners, including actin, emerin, and SREBP1, but how these interactions are regulated is unknown. We report small ubiquitin-lik...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The American Society for Cell Biology
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564541/ https://www.ncbi.nlm.nih.gov/pubmed/23243001 http://dx.doi.org/10.1091/mbc.E12-07-0527 |