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RNA polymerase II progression through H3K27me3-enriched gene bodies requires JMJD3 histone demethylase

JMJD3 H3K27me3 demethylase plays an important role in the transcriptional response to different signaling pathways; however, the mechanism by which it facilitates transcription has been unclear. Here we show that JMJD3 regulates transcription of transforming growth factor β (TGFβ)–responsive genes b...

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Detalles Bibliográficos
Autores principales: Estarás, Conchi, Fueyo, Raquel, Akizu, Naiara, Beltrán, Sergi, Martínez-Balbás, Marian A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564542/
https://www.ncbi.nlm.nih.gov/pubmed/23243002
http://dx.doi.org/10.1091/mbc.E12-07-0561