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Early dysregulation of the memory CD8(+) T cell repertoire leads to compromised immune responses to secondary viral infection in the aged

BACKGROUND: Virus-specific memory CD8(+) T cells persist long after infection is resolved and are important for mediating recall responses to secondary infection. Although the number of memory T cells remains relatively constant over time, little is known about the overall stability of the memory T...

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Detalles Bibliográficos
Autores principales: Connor, Lisa M, Kohlmeier, Jacob E, Ryan, Lynn, Roberts, Alan D, Cookenham, Tres, Blackman, Marcia A, Woodland, David L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564731/
https://www.ncbi.nlm.nih.gov/pubmed/23244347
http://dx.doi.org/10.1186/1742-4933-9-28