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Trisomy 8: a common finding in mouse embryonic stem (ES) cell lines
BACKGROUND: Obtaining a germ cell line is one of the most important steps in developing a transgenic or knockout mouse with a targeted mutated gene of interest. A common problem with this technology is that embryonic stem (ES) cells often lack, or are extremely inefficient at, germ line transmission...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564830/ https://www.ncbi.nlm.nih.gov/pubmed/23320952 http://dx.doi.org/10.1186/1755-8166-6-3 |