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Trisomy 8: a common finding in mouse embryonic stem (ES) cell lines

BACKGROUND: Obtaining a germ cell line is one of the most important steps in developing a transgenic or knockout mouse with a targeted mutated gene of interest. A common problem with this technology is that embryonic stem (ES) cells often lack, or are extremely inefficient at, germ line transmission...

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Detalles Bibliográficos
Autores principales:	Kim, Young Mi, Lee, Ji-Yun, Xia, Lijun, Mulvihill, John J, Li, Shibo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2013
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564830/ https://www.ncbi.nlm.nih.gov/pubmed/23320952 http://dx.doi.org/10.1186/1755-8166-6-3

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