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A Gly98Val Mutation in the N-Myc Downstream Regulated Gene 1 (NDRG1) in Alaskan Malamutes with Polyneuropathy

The first cases of early-onset progressive polyneuropathy appeared in the Alaskan Malamute population in Norway in the late 1970s. Affected dogs were of both sexes and were ambulatory paraparetic, progressing to non-ambulatory tetraparesis. On neurologic examination, affected dogs displayed predomin...

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Detalles Bibliográficos
Autores principales: Bruun, Camilla S., Jäderlund, Karin H., Berendt, Mette, Jensen, Kristine B., Spodsberg, Eva H., Gredal, Hanne, Shelton, G. Diane, Mickelson, James R., Minor, Katie M., Lohi, Hannes, Bjerkås, Inge, Stigen, Øyvind, Espenes, Arild, Rohdin, Cecilia, Edlund, Rebecca, Ohlsson, Jennie, Cizinauskas, Sigitas, Leifsson, Páll S., Drögemüller, Cord, Moe, Lars, Cirera, Susanna, Fredholm, Merete
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564917/
https://www.ncbi.nlm.nih.gov/pubmed/23393557
http://dx.doi.org/10.1371/journal.pone.0054547