Genetically Engineered Excitable Cardiac Myofibroblasts Coupled to Cardiomyocytes Rescue Normal Propagation and Reduce Arrhythmia Complexity in Heterocellular Monolayers

RATIONALE AND OBJECTIVE: The use of genetic engineering of unexcitable cells to enable expression of gap junctions and inward rectifier potassium channels has suggested that cell therapies aimed at establishing electrical coupling of unexcitable donor cells to host cardiomyocytes may be arrhythmogen...

Descripción completa

Detalles Bibliográficos
Autores principales: Hou, Luqia, Hu, Bin, Jalife, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564921/
https://www.ncbi.nlm.nih.gov/pubmed/23393574
http://dx.doi.org/10.1371/journal.pone.0055400

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564921/
https://www.ncbi.nlm.nih.gov/pubmed/23393574
http://dx.doi.org/10.1371/journal.pone.0055400

Ejemplares similares