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Functional expression of a proton-coupled organic cation (H(+)/OC) antiporter in human brain capillary endothelial cell line hCMEC/D3, a human blood–brain barrier model
BACKGROUND: Knowledge of the molecular basis and transport function of the human blood–brain barrier (BBB) is important for not only understanding human cerebral physiology, but also development of new central nervous system (CNS)-acting drugs. However, few studies have been done using human brain c...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564923/ https://www.ncbi.nlm.nih.gov/pubmed/23351963 http://dx.doi.org/10.1186/2045-8118-10-8 |