Long-Term Inhibition of Xanthine Oxidase by Febuxostat Does Not Decrease Blood Pressure in Deoxycorticosterone Acetate (DOCA)-Salt Hypertensive Rats

Xanthine oxidase and its products, uric acid and ROS, have been implicated in the pathogenesis of cardiovascular disease, such as hypertension. We have previously reported that allopurinol inhibition of XO does not alter the progression of deoxycorticosterone acetate (DOCA)-salt hypertension in rats...

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Detalles Bibliográficos
Autores principales: Szasz, Theodora, Davis, Robert Patrick, Garver, Hannah S., Burnett, Robert J., Fink, Gregory D., Watts, Stephanie W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564945/
https://www.ncbi.nlm.nih.gov/pubmed/23393607
http://dx.doi.org/10.1371/journal.pone.0056046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564945/
https://www.ncbi.nlm.nih.gov/pubmed/23393607
http://dx.doi.org/10.1371/journal.pone.0056046

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