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Fosmid-Based Structure-Function Analysis Reveals Functionally Distinct Domains in the Cytoplasmic Domain of Drosophila Crumbs

The evolutionarily conserved transmembrane protein Crumbs is required for epithelial polarity and morphogenesis in the embryo, control of tissue size in imaginal discs and morphogenesis of photoreceptor cells, and prevents light-dependent retinal degeneration. The small cytoplasmic domain contains t...

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Detalles Bibliográficos
Autores principales: Klose, Sven, Flores-Benitez, David, Riedel, Falko, Knust, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564977/
https://www.ncbi.nlm.nih.gov/pubmed/23390593
http://dx.doi.org/10.1534/g3.112.005074