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Caenorhabditis elegans POT-1 and POT-2 Repress Telomere Maintenance Pathways
Telomeres are composed of simple tandem DNA repeats that protect the ends of linear chromosomes from replicative erosion or inappropriate DNA damage response mechanisms. The mammalian Protection Of Telomeres (POT1) protein interacts with single-stranded telomeric DNA and can exert positive and negat...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3564990/ https://www.ncbi.nlm.nih.gov/pubmed/23390606 http://dx.doi.org/10.1534/g3.112.004440 |