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Nucleosome mobilization by ISW2 requires the concerted action of the ATPase and SLIDE domains
The ISWI family of ATP-dependent chromatin remodelers represses transcription by changing nucleosome positioning. The interactions with extranucleosomal DNA and the requirement of a minimal length of extranucleosomal DNA by ISWI mediate the spacing of nucleosomes. ISW2 from Saccharomyces cerevisiae,...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565048/ https://www.ncbi.nlm.nih.gov/pubmed/23334290 http://dx.doi.org/10.1038/nsmb.2486 |