Evolutionary conservation of codon optimality reveals hidden signatures of co-translational folding

The choice of codons can influence local translation kinetics during protein synthesis. Whether codon preference is linked to co-translational regulation of polypeptide folding remains unclear. Here, we derive a revised translational efficiency scale that incorporates the competition between tRNA su...

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Detalles Bibliográficos
Autores principales: Pechmann, Sebastian, Frydman, Judith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565066/
https://www.ncbi.nlm.nih.gov/pubmed/23262490
http://dx.doi.org/10.1038/nsmb.2466

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565066/
https://www.ncbi.nlm.nih.gov/pubmed/23262490
http://dx.doi.org/10.1038/nsmb.2466

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