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Evolutionary conservation of codon optimality reveals hidden signatures of co-translational folding
The choice of codons can influence local translation kinetics during protein synthesis. Whether codon preference is linked to co-translational regulation of polypeptide folding remains unclear. Here, we derive a revised translational efficiency scale that incorporates the competition between tRNA su...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565066/ https://www.ncbi.nlm.nih.gov/pubmed/23262490 http://dx.doi.org/10.1038/nsmb.2466 |