Inhibition of cancer cell proliferation by 5-fluoro-2'-deoxycytidine, a DNA methylation inhibitor, through activation of DNA damage response pathway

Multiple epigenetic changes, including alterations in DNA methylation occur during tumorigenesis. Various inhibitors of DNA methylation have been developed to prevent proliferation of cancer cells. 5-fluoro-2(′)-deoxycytidine (FCdR) is one such DNA methylation inhibitor, which is currently in phase...

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Detalles Bibliográficos
Autores principales: Zhao, Quanyi, Fan, Jiadong, Hong, Wei, Li, Lianyun, Wu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing AG 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565089/
https://www.ncbi.nlm.nih.gov/pubmed/23397046
http://dx.doi.org/10.1186/2193-1801-1-65

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565089/
https://www.ncbi.nlm.nih.gov/pubmed/23397046
http://dx.doi.org/10.1186/2193-1801-1-65

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