The promoter search mechanism of E. coli RNA polymerase is dominated by three–dimensional diffusion

Gene expression, DNA replication, and genome maintenance are all initiated by proteins that must recognize specific targets from among a vast excess of nonspecific DNA. For example, to initiate transcription, E. coli RNA polymerase must locate promoter sequences, which comprise <2% of the bacteri...

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Detalles Bibliográficos
Autores principales: Wang, Feng, Redding, Sy, Finkelstein, Ilya J., Gorman, Jason, Reichman, David R., Greene, Eric C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565103/
https://www.ncbi.nlm.nih.gov/pubmed/23262491
http://dx.doi.org/10.1038/nsmb.2472

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565103/
https://www.ncbi.nlm.nih.gov/pubmed/23262491
http://dx.doi.org/10.1038/nsmb.2472

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