Intrathecal Lamotrigine Attenuates Antinociceptive Morphine Tolerance and Suppresses Spinal Glial Cell Activation in Morphine-Tolerant Rats

Glial cells play a critical role in morphine tolerance, resulting from repeated administration of morphine. Both the development and the expression of tolerance are suppressed by the analgesic lamotrigine. This study investigated the relationship between the ability of lamotrigine to maintain the an...

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Detalles Bibliográficos
Autores principales: Jun, In-Gu, Kim, Sung-Hoon, Yoon, Yang-In, Park, Jong-Yeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Academy of Medical Sciences 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565144/
https://www.ncbi.nlm.nih.gov/pubmed/23399922
http://dx.doi.org/10.3346/jkms.2013.28.2.300

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565144/
https://www.ncbi.nlm.nih.gov/pubmed/23399922
http://dx.doi.org/10.3346/jkms.2013.28.2.300

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