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A longitudinal pilot proton MRS investigation of the manic and euthymic states of bipolar disorder

Several lines of evidence implicate dysfunction in brain energy production as a key component of bipolar disorder. In particular, elevated brain lactate levels observed in this condition suggest a shift from aerobic to anaerobic metabolism, possibly as a result of mitochondrial abnormalities. Most p...

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Detalles Bibliográficos
Autores principales: Brady, R O, Cooper, A, Jensen, J E, Tandon, N, Cohen, B, Renshaw, P, Keshavan, M, Öngür, D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565206/
https://www.ncbi.nlm.nih.gov/pubmed/22968227
http://dx.doi.org/10.1038/tp.2012.84