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Advanced Urothelial Carcinoma: Overcoming Treatment Resistance through Novel Treatment Approaches
The current standard of care for metastatic urothelial carcinoma is cisplatin-based chemotherapy but treatment is generally not curative. Mechanisms of resistance to conventional cytotoxic regimens include tumor cell drug efflux pumps, intracellular anti-oxidants, and enhanced anti-apoptotic signali...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565214/ https://www.ncbi.nlm.nih.gov/pubmed/23390417 http://dx.doi.org/10.3389/fphar.2013.00003 |