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Advanced Urothelial Carcinoma: Overcoming Treatment Resistance through Novel Treatment Approaches

The current standard of care for metastatic urothelial carcinoma is cisplatin-based chemotherapy but treatment is generally not curative. Mechanisms of resistance to conventional cytotoxic regimens include tumor cell drug efflux pumps, intracellular anti-oxidants, and enhanced anti-apoptotic signali...

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Detalles Bibliográficos
Autores principales:	Bambury, Richard M., Rosenberg, Jonathan E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2013
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565214/ https://www.ncbi.nlm.nih.gov/pubmed/23390417 http://dx.doi.org/10.3389/fphar.2013.00003

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