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Role of Carnitine Acetyl Transferase in Regulation of Nitric Oxide Signaling in Pulmonary Arterial Endothelial Cells

Congenital heart defects with increased pulmonary blood flow (PBF) result in pulmonary endothelial dysfunction that is dependent, at least in part, on decreases in nitric oxide (NO) signaling. Utilizing a lamb model with left-to-right shunting of blood and increased PBF that mimics the human disease...

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Detalles Bibliográficos
Autores principales: Sharma, Shruti, Sun, Xutong, Agarwal, Saurabh, Rafikov, Ruslan, Dasarathy, Sridevi, Kumar, Sanjiv, Black, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565262/
https://www.ncbi.nlm.nih.gov/pubmed/23344032
http://dx.doi.org/10.3390/ijms14010255