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Apoptosis is Induced in Cancer Cells via the Mitochondrial Pathway by the Novel Xylocydine-Derived Compound JRS-15

The novel compound JRS-15 was obtained through the chemical modification of xylocydine. JRS-15 exhibited much stronger cytotoxic and pro-apoptotic activity than its parent compound in various cancer cell lines, with IC(50) values in HeLa, HepG2, SK-HEP-1, PC-3M and A549 cells ranging from 12.42 to 2...

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Detalles Bibliográficos
Autores principales:	Sun, Chao, Guo, Xiao-Xi, Zhu, Dan, Xiao, Chuan, Bai, Xiao, Li, Yang, Zhan, Zhuo, Li, Xiang-Long, Song, Zhi-Guang, Jin, Ying-Hua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565295/ https://www.ncbi.nlm.nih.gov/pubmed/23344045 http://dx.doi.org/10.3390/ijms14010850

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