The Role of Altered Nucleotide Excision Repair and UVB-Induced DNA Damage in Melanomagenesis

UVB radiation is the most mutagenic component of the UV spectrum that reaches the earth’s surface and causes the development of DNA damage in the form of cyclobutane pyrimidine dimers and 6-4 photoproducts. UV radiation usually results in cellular death, but if left unchecked, it can affect DNA inte...

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Detalles Bibliográficos
Autores principales: Budden, Timothy, Bowden, Nikola A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565312/
https://www.ncbi.nlm.nih.gov/pubmed/23303275
http://dx.doi.org/10.3390/ijms14011132

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565312/
https://www.ncbi.nlm.nih.gov/pubmed/23303275
http://dx.doi.org/10.3390/ijms14011132

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