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The Role of Altered Nucleotide Excision Repair and UVB-Induced DNA Damage in Melanomagenesis
UVB radiation is the most mutagenic component of the UV spectrum that reaches the earth’s surface and causes the development of DNA damage in the form of cyclobutane pyrimidine dimers and 6-4 photoproducts. UV radiation usually results in cellular death, but if left unchecked, it can affect DNA inte...
Autores principales: | Budden, Timothy, Bowden, Nikola A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565312/ https://www.ncbi.nlm.nih.gov/pubmed/23303275 http://dx.doi.org/10.3390/ijms14011132 |
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