Effect of Repetitive Lysine-Tryptophan Motifs on the Eukaryotic Membrane

In a previous study, we synthesized a series of peptides containing simple sequence repeats, (KW)(n)–NH(2) (n = 2,3,4 and 5) and determined their antimicrobial and hemolytic activities, as well as their mechanism of antimicrobial action. However, (KW)(5) showed undesirable cytotoxicity against RBC c...

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Detalles Bibliográficos
Autores principales: Gopal, Ramamourthy, Lee, Jong Kook, Lee, Jun Ho, Kim, Young Gwon, Oh, Gwang Chae, Seo, Chang Ho, Park, Yoonkyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565372/
https://www.ncbi.nlm.nih.gov/pubmed/23340654
http://dx.doi.org/10.3390/ijms14012190

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565372/
https://www.ncbi.nlm.nih.gov/pubmed/23340654
http://dx.doi.org/10.3390/ijms14012190

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