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Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder

Major depressive disorder (MDD) is a common psychiatric illness characterized by low mood and loss of interest in pleasurable activities. Despite years of effort, recent genome-wide association studies (GWAS) have identified few susceptibility variants or genes that are robustly associated with MDD....

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Detalles Bibliográficos
Autores principales: Lee, P H, Perlis, R H, Jung, J-Y, Byrne, E M, Rueckert, E, Siburian, R, Haddad, S, Mayerfeld, C E, Heath, A C, Pergadia, M L, Madden, P A F, Boomsma, D I, Penninx, B W, Sklar, P, Martin, N G, Wray, N R, Purcell, S M, Smoller, J W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565768/
https://www.ncbi.nlm.nih.gov/pubmed/23149448
http://dx.doi.org/10.1038/tp.2012.95