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Multi-locus genome-wide association analysis supports the role of glutamatergic synaptic transmission in the etiology of major depressive disorder
Major depressive disorder (MDD) is a common psychiatric illness characterized by low mood and loss of interest in pleasurable activities. Despite years of effort, recent genome-wide association studies (GWAS) have identified few susceptibility variants or genes that are robustly associated with MDD....
Autores principales: | Lee, P H, Perlis, R H, Jung, J-Y, Byrne, E M, Rueckert, E, Siburian, R, Haddad, S, Mayerfeld, C E, Heath, A C, Pergadia, M L, Madden, P A F, Boomsma, D I, Penninx, B W, Sklar, P, Martin, N G, Wray, N R, Purcell, S M, Smoller, J W |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565768/ https://www.ncbi.nlm.nih.gov/pubmed/23149448 http://dx.doi.org/10.1038/tp.2012.95 |
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