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Evaluation of characteristics of CD44(+)CD117(+) ovarian cancer stem cells in three dimensional basement membrane extract scaffold versus two dimensional monocultures

BACKGROUND: Cancer stem cells (CSCs) are thought to be capable of surviving conventional chemotherapeutic treatments because the cells have more resistant to anticancer drugs than common cancer cells. Most in vitro studies in experimental cancer cells have been done in a two-dimensional (2D) monocul...

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Detalles Bibliográficos
Autores principales: Chen, Junsong, Wang, Jing, Chen, Dengyu, Yang, Jie, Yang, Cuiping, Zhang, Yunxia, Zhang, Hongyi, Dou, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565868/
https://www.ncbi.nlm.nih.gov/pubmed/23368632
http://dx.doi.org/10.1186/1471-2121-14-7