Differential requirement for Hoxa9 in the development and differentiation of B, NK, and DC-lineage cells from Flt3+ multipotential progenitors

Hoxa9 is a homeodomain transcription factor important for the generation of Flt3+hiIL-7R- lymphoid biased-multipotential progenitors, Flt3+IL-7R+ common lymphoid progenitors (CLPs), and B cell precursors (BCP) in bone marrow (BM). In addition to B-cell, Flt3+IL-7R+ CLPs possess NK and DC development...

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Detalles Bibliográficos
Autores principales: Gwin, Kimberly, Dolence, Joseph J, Shapiro, Mariya B, Medina, Kay L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565875/
https://www.ncbi.nlm.nih.gov/pubmed/23363389
http://dx.doi.org/10.1186/1471-2172-14-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565875/
https://www.ncbi.nlm.nih.gov/pubmed/23363389
http://dx.doi.org/10.1186/1471-2172-14-5

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