Transition of a microRNA from Repressing to Activating Translation Depending on the Extent of Base Pairing with the Target

MicroRNAs are major post-transcriptional regulators of gene expression. Here we show in the ancient protozoan Giardia lamblia a snoRNA-derived 26-nucleotide microRNA, miR3, which represses the translation of histone H2A mRNA containing an imperfect target but enhances translation when the target is...

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Detalles Bibliográficos
Autores principales: Saraiya, Ashesh A., Li, Wei, Wang, Ching C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565978/
https://www.ncbi.nlm.nih.gov/pubmed/23405193
http://dx.doi.org/10.1371/journal.pone.0055672

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3565978/
https://www.ncbi.nlm.nih.gov/pubmed/23405193
http://dx.doi.org/10.1371/journal.pone.0055672

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