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Antiplatelet Agents Can Promote Two-Peaked Thrombin Generation in Platelet Rich Plasma: Mechanism and Possible Applications

BACKGROUND: Thrombin generation assay is a convenient and widely used method for analysis of the blood coagulation system status. Thrombin generation curve (TGC) is usually bell-shaped with a single peak, but there are exceptions. In particular, TGC in platelet-rich plasma (PRP) can sometimes have t...

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Detalles Bibliográficos
Autores principales: Tarandovskiy, Ivan D., Artemenko, Elena O., Panteleev, Mikhail A., Sinauridze, Elena I., Ataullakhanov, Fazoil I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566002/
https://www.ncbi.nlm.nih.gov/pubmed/23405196
http://dx.doi.org/10.1371/journal.pone.0055688