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Exposure of Chlorpromazine to 266 nm Laser Beam Generates New Species with Antibacterial Properties: Contributions to Development of a New Process for Drug Discovery

INTRODUCTION: Phenothiazines when exposed to white light or to UV radiation undergo a variety of reactions that result in degradation of parental compound and formation of new species. This process is slow and may be sped up with exposure to high energy light such as that produced by a laser. METHOD...

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Detalles Bibliográficos
Autores principales: Pascu, Mihail Lucian, Danko, Balazs, Martins, Ana, Jedlinszki, Nikoletta, Alexandru, Tatiana, Nastasa, Viorel, Boni, Mihai, Militaru, Andra, Andrei, Ionut Relu, Staicu, Angela, Hunyadi, Attila, Fanning, Seamus, Amaral, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566004/
https://www.ncbi.nlm.nih.gov/pubmed/23405212
http://dx.doi.org/10.1371/journal.pone.0055767