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Exposure of Chlorpromazine to 266 nm Laser Beam Generates New Species with Antibacterial Properties: Contributions to Development of a New Process for Drug Discovery
INTRODUCTION: Phenothiazines when exposed to white light or to UV radiation undergo a variety of reactions that result in degradation of parental compound and formation of new species. This process is slow and may be sped up with exposure to high energy light such as that produced by a laser. METHOD...
Autores principales: | Pascu, Mihail Lucian, Danko, Balazs, Martins, Ana, Jedlinszki, Nikoletta, Alexandru, Tatiana, Nastasa, Viorel, Boni, Mihai, Militaru, Andra, Andrei, Ionut Relu, Staicu, Angela, Hunyadi, Attila, Fanning, Seamus, Amaral, Leonard |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566004/ https://www.ncbi.nlm.nih.gov/pubmed/23405212 http://dx.doi.org/10.1371/journal.pone.0055767 |
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