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HDAC6 Deacetylase Activity Is Required for Hypoxia-Induced Invadopodia Formation and Cell Invasion

Despite significant progress in the cancer field, tumor cell invasion and metastasis remain a major clinical challenge. Cell invasion across tissue boundaries depends largely on extracellular matrix degradation, which can be initiated by formation of actin-rich cell structures specialized in matrix...

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Detalles Bibliográficos
Autores principales: Arsenault, Dominique, Brochu-Gaudreau, Karine, Charbonneau, Martine, Dubois, Claire M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566011/
https://www.ncbi.nlm.nih.gov/pubmed/23405166
http://dx.doi.org/10.1371/journal.pone.0055529